Oxygen Consumption During Maximal Exercise in Fischer 344 x Brown Norway F1 Hybrid Rats
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چکیده
منابع مشابه
Fiber atrophy and hypertrophy in skeletal muscles of late middle-aged Fischer 344 x Brown Norway F1-hybrid rats.
We examined young adult and late middle-aged male rats to test the hypothesis that gastrocnemius (a locomotor muscle) demonstrates reduced fiber size with aging, whereas soleus (a postural muscle) demonstrates atrophy of some fibers and compensatory hypertrophy in other fibers. Although body mass was greater in late middle-aged animals, mass was reduced in gastrocnemius but not soleus muscle. I...
متن کاملAge-related changes in cardiac structure and function in Fischer 344 x Brown Norway hybrid rats.
The effects of aging on cardiovascular function and cardiac structure were determined in a rat model recommended for gerontological studies. A cross-sectional analysis assessed cardiac changes in male Fischer 344 x Brown Norway F1 hybrid rats (FBN) from adulthood to the very aged (n = 6 per 12-, 18-, 21-, 24-, 27-, 30-, 33-, 36-, and 39-mo-old group). Rats underwent echocardiographic and hemody...
متن کاملImpact of genetic background and aging on mesenteric collateral growth capacity in Fischer 344, Brown Norway, and Fischer 344 x Brown Norway hybrid rats.
Available studies indicate that both genetic background and aging influence collateral growth capacity, but it is not known how their combination affects collateral growth. We evaluated collateral growth induced by ileal artery ligation in Fischer 344 (F344), Brown Norway (BN), and the first generation hybrid of F344 x BN (F1) rats available for aging research from the National Institute on Agi...
متن کاملAge-associated changes in hearts of male Fischer 344/Brown Norway F1 rats.
Aging is associated with left ventricular hypertrophy, dilatation, and fibrosis of the heart. The Fischer 344/Brown Norway F1 (F344/BNF1) rat is recommended for age-related studies by the National Institutes on Aging because this hybrid rat lives longer and has a lower rate of pathological conditions than inbred rats. However, little is known about age-associated changes in cardiac and aortic f...
متن کاملAge-related changes in cardiac structure and function in Fischer 344 Brown Norway hybrid rats
Hacker, Timothy A., Susan H. McKiernan, Pamela S. Douglas, Jonathan Wanagat, and Judd M. Aiken. Age-related changes in cardiac structure and function in Fischer 344 Brown Norway hybrid rats. Am J Physiol Heart Circ Physiol 290: H304–H311, 2006. First published September 2, 2005; doi:10.1152/ajpheart.00290.2005.— The effects of aging on cardiovascular function and cardiac structure were determin...
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ژورنال
عنوان ژورنال: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
سال: 2004
ISSN: 1079-5006,1758-535X
DOI: 10.1093/gerona/59.8.b801